Apuzzo, MLJ. (2002). Pharmacological therapy after acute cervical spinal cord injury. Neurosurgery, 50(3), Supplement, 63-72.
Of all the articles in the supplement of Neurosurgery this topic remains the most controversial. This is again an evidenced based approach for the use of methylprednisolone in the management of acute spinal cord injury. If you are looking to change or modify you existing spinal cord injury protocol this is a must reading. In this article methylprednisolone is recommended only as an option in the treatment of patients with acute spinal cord injuries that should be undertaken with the knowledge that the evidence suggesting harmful side effects is more consistent than any suggestion of clinical benefit.